Article ID Journal Published Year Pages File Type
5279973 Tetrahedron Letters 2007 4 Pages PDF
Abstract

An efficient stereoselective synthesis of (+)-deoxoprosophylline from readily available p-anisaldehyde is described. Key steps in the synthesis include the stereoselective amination of anti-1,2-dibenzyl ether using chlorosulfonyl isocyanate, intermolecular olefination, and Pd-catalyzed intramolecular cyclization.

Graphical abstractDownload full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , ,