| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5279996 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A series of 2-(pyrazolo[1,5-a]pyrimidin-5-yl)benzoic acids 5 has been prepared by a novel protocol that uses the fusion method between 5-amino-1H-pyrazoles 4 and 3-(3-oxo-2-benzofuran-1(3H)-ylidene)pentane-2,4-dione 3. The use of this novel protocol renders good to excellent yields along with short reaction times. In addition, this solvent-free cyclocondensation proceeds in a regiospecific fashion by intramolecular ring opening of the furane ring in a Michael-type reaction.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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