Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280032 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
The palladium-catalyzed allene transformation reaction from propargylic amines proceeded in the presence of Pd2(dba)3·CHCl3 (5 mol %) and (C6F5)2PC2H4P(C6F5)2 (10 mol %) in CHCl3 at room temperature to give the corresponding allenes in good to high yields. Dicyclohexyl groups substituted on the nitrogen of propargylic amines were found to be effective for the current transformation and the conjugated ene-allenes 4 were synthesized from the corresponding propargylic amines 3 under mild conditions.
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Authors
Hiroyuki Nakamura, Satoshi Tashiro, Takaya Kamakura,