| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280158 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A series of allenic ketones react with a glyoxylate-derived imine in the presence of MgBr2 through an aza-Morita-Baylis-Hillman (MBH) reaction. The isolation of a variety of unnatural amino acids with unique allene-containing functional groups provides a conceptually new application of the aza-MBH. The reaction scope and preliminary mechanistic investigations are discussed.
Graphical abstractDownload full-size image
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lindsey O. Davis, Suzanne L. Tobey,