Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280270 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
Rigid linkers of variable length were synthesized and used to connect two NDP-α-MSH ligands. The linkers were incorporated by solid-phase synthesis. Biological evaluations indicate that there is virtually no effect of these linkers on ligand binding to the human melanocortin 4 receptor.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yasunari Monguchi, Josef Vagner, Heather L. Handl, Umasish Jana, Lucinda J. Begay, Victor J. Hruby, Robert J. Gillies, Eugene A. Mash,