| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280274 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
Novel base-discriminating fluorescent (BDF) nucleoside, 8-fluorescence-labeled adenosine derivative (8PyA), was developed for the detection of thymine base on a target DNA. The BDF nucleoside was incorporated into oligodeoxynucleotides by post-synthetic modification. BDF probes containing 8PyA selectively emit fluorescence only when the base opposite BDF nucleoside is thymine and act as effective reporter probes for homogeneous SNP typing.
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Authors
Yoshio Saito, Kazuo Hanawa, Kaori Motegi, Kenji Omoto, Akimitsu Okamoto, Isao Saito,