| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280301 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
The first total synthesis and structural determination of YCM1008A, a Ca2+ signaling inhibitor, have been achieved. The N-methoxy pyrano-pyridone moiety was synthesized by successive O- and N-conjugate additions with diketoamide 15. The absolute structure was determined to be (2R,3R,4S,8â²R)-configuration.
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Authors
Kuniaki Tatsuta, Takahiro Yamaguchi, Yusuke Tsuda, Yumiko Yamaguchi, Nobutaka Hattori, Hiroshi Nagai, Seijiro Hosokawa,