Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280400 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
The first synthesis of rubrolide L, a marine ascidian butenolide and a potent inhibitor of human aldose reductase, has been achieved by two tactically distinct pathways in 4-5 steps and 37-42% overall yield from commercially available 3-chlorotetronic acid.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
John Boukouvalas, Lucas C. McCann,