| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280401 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
5-Methoxy-3H-naphtho[2,1,8-mna]xanthen-3-one (musafluorone, 1), the only naphthoxanthenone reported so far from Musaceae, was synthesized starting from 2-naphthol in nine steps and resulted in an overall yield of 3%. Grignard addition of phenylmagnesium bromide to 4-methoxyperinaphthenone afforded the corresponding 4-methoxy-9-phenylphenalenone which, after epoxidation and methyl transposition, was subjected to a photochemical cyclization procedure to furnish 1.
Graphical abstractMusafluorone was synthesized using a nine-step procedure including a Grignard addition and a photochemical cyclization.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Luisa Duque, Catalina Restrepo, Jairo Sáez, Jesús Gil, Bernd Schneider, Felipe Otálvaro,