Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280474 | Tetrahedron Letters | 2005 | 4 Pages |
Abstract
The regioselectivity of the Pd-catalyzed allylic substitution of cyclic substrates possessing an adjacent amide functional group was investigated. With imide-like nucleophiles, six-membered ring substrates were found to proceed with a high level of regiodirection whereas hydrogen-bond directed addition was not a significant factor in the five-membered ring substrates.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Gregory R. Cook, Manjusha Saraswathiamma,