| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280488 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
Reaction of 1-substituted 3-alkenyl-1H-indoles with an equimolar amount of trifluoroacetic acid in dichloromethane gave cyclic dimers, 1,3-trans-N,Nâ²-disubstituted cyclopent[b]indoles, in 53-84% yields as sole products through an acid-mediated stereoselective cyclo-dimerization process. The structure of the cyclic dimer derived from 3-cyclopentylidenemethyl-1-methyl-1H-indole was elucidated by X-ray crystallographic analysis.
Related Topics
Physical Sciences and Engineering
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![A novel TFA-mediated cyclo-dimerization of 1-substituted 3-alkenylindole derivatives to cyclopent[b]indoles](/preview/png/5280488.png "First Page Preview: A novel TFA-mediated cyclo-dimerization of 1-substituted 3-alkenylindole derivatives to cyclopent[b]indoles")
Authors
Ikuo Kawasaki, Masami Terano, Ai Kurume, Satoko Hara, Masayuki Yamashita, Shunsaku Ohta,