Article ID Journal Published Year Pages File Type
5280516 Tetrahedron Letters 2007 4 Pages PDF
Abstract

Reduction of biotin sulfone derivatives leads to 2-epi-biotin analogs. The stereochemistry of the side chain at C2 can be simply deduced from the diagnostic chemical shift pattern of the benzylic protons, rather than through the conventional analysis of the coupling constants using the empirical Karplus equation.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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