Article ID Journal Published Year Pages File Type
5280522 Tetrahedron Letters 2007 5 Pages PDF
Abstract

An iterative method for the synthesis of C2-C4′ linked poly-oxazoles has been developed. This efficient two-step repetitive process includes TBS-iodine exchange reaction and Suzuki-Miyaura cross-coupling reaction with oxazolylboronate 8, which allows appending a bis-oxazole moiety per each iteration. The synthesis of bis-, tris-, tetrakis-, pentakis-, and hexakis-oxazoles (10, 14, 22, 18, and 24) was achieved starting from the common intermediate 7 in 1-5 steps.

Graphical abstractAn iterative method for the synthesis of C2-C4′ linked poly-oxazoles has been developed.Download full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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