Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280522 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
An iterative method for the synthesis of C2-C4â² linked poly-oxazoles has been developed. This efficient two-step repetitive process includes TBS-iodine exchange reaction and Suzuki-Miyaura cross-coupling reaction with oxazolylboronate 8, which allows appending a bis-oxazole moiety per each iteration. The synthesis of bis-, tris-, tetrakis-, pentakis-, and hexakis-oxazoles (10, 14, 22, 18, and 24) was achieved starting from the common intermediate 7 in 1-5 steps.
Graphical abstractAn iterative method for the synthesis of C2-C4â² linked poly-oxazoles has been developed.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hiroshi Araki, Tadashi Katoh, Munenori Inoue,