| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280609 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
We report that solid-phase hydrothiolysis is an efficient method to convert resin-bound peptide thioesters to thioacids in aqueous buffer by using a total PEG-based resin. Also demonstrated is the use of the so-prepared peptide thioacids in chemoselective amide bond formation reactions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaohong Zhang, Xiao-Wei Lu, Chuan-Fa Liu,