Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280640 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
The alkoxycarbonylation of α,β-unsaturated amides proceeded efficiently and regioselectivity to give Ï-amido esters with complete conversion in the presence of the catalyst system: Pd(PPh3)2Cl2/MeOH/CO/H2O. The reaction was successfully applied to the alkoxycarbonylation of bis-acrylamides yielding, selectively, the corresponding di-Ï-amido esters. These mono and di-Ï-amido esters have been used as precursors for the synthesis of N-substituted cyclic succinimides in moderate to high yields.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rami Suleiman, Bassam El Ali,