Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280646 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A mild, general, convenient and practical methodology for the selective copper-mediated mono N-arylation of unprotected 2-imidazolidinone was developed. Strong electron-donating groups and free hydroxy and amino groups on the aryl iodide substrates were well tolerated. The use of n-butanol as the solvent for the copper-catalysed mono-arylation of 2-imidazolidinone is unprecedented.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Paolo Stabile, Alessandro Lamonica, Arianna Ribecai, Damiano Castoldi, Giuseppe Guercio, Ornella Curcuruto,