| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280649 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
Direct coupling of 1,1-dibromoethenes with 2-aminophenols had been achieved to form the corresponding benzoxazoles under mildly basic reaction conditions. A variety of substituted 2-aminophenols provided the desired products in moderate to good yields. Even though 1,1-dibromoethenes have to be derived from arylcarboxaldehydes or glyoxalate for the reactions, this method still provides a new route to the preparation of benzoxazoles, complementing to existing synthetic strategies.
Graphical abstractDirect coupling of 1,1-dibromoethenes with 2-aminophenols had been achieved to form corresponding benzoxazoles under mildly basic reaction conditions.Download full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kemei Tao, Jianlong Zheng, Zhaogui Liu, Wang Shen, Jiancun Zhang,