| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280683 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
3,6-Difluoro-3-deazapurine ribonucleoside analogs underwent direct SNAr amination reactions with liquid ammonia to give 3-fluoro-3-deazaadenosine analogs in excellent yield; in contrast, 6-chloro-3-fluoro-3-deazapurine nucleosides were inert.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Direct SNAr amination of fluorinated imidazo[4,5-c]pyridine nucleosides: efficient syntheses of 3-fluoro-3-deazaadenosine analogs](/preview/png/5280683.png "First Page Preview: Direct SNAr amination of fluorinated imidazo[4,5-c]pyridine nucleosides: efficient syntheses of 3-fluoro-3-deazaadenosine analogs")
Authors
Kandasamy Sakthivel, P. Dan Cook,