| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280685 | Tetrahedron Letters | 2005 | 5 Pages |
Abstract
The application of a unique tandem radical-initiated, Brönsted acid-catalysed, skeletal rearrangement of bicyclo[2.2.2]lactones provides a novel route towards Corey's lactone 2. The strategy also features a high-pressure promoted inverse electron-demand Diels-Alder (IEDDA) reaction of 3-carbomethoxy-2-pyrone (3-CMP), which proceeds with complete regio- and diastereocontrol.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
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Authors
BenoıËt Augustyns, Nuno Maulide, István E. Markó,