| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5280841 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A stereoselective synthesis of selenosteroids 4 and 5 has been achieved. Starting from commercial available cholesterol 1, followed by asymmetric epoxidation, and subsequently, by stereoselective epoxide ring opening, employing a selenium nucleophilic species, the correspondent products were afforded in high yields. The compounds were being evaluated for their biological activity and as a chiral pool for asymmetric transformations.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Oscar E.D. Rodrigues, Diego de Souza, Letiére C. Soares, Luciano Dornelles, Robert A. Burrow, Helmoz R. Appelt, Camila F. Alves, Diego Alves, Antonio L. Braga,