Article ID Journal Published Year Pages File Type
5280870 Tetrahedron Letters 2010 4 Pages PDF
Abstract
A simple and efficient total synthesis of ellipticine was developed via the Suzuki-Miyaura coupling of sterically sensitive 2-hydroxybenzeneboronic acid with a multifunctional aryl halide using Pd(OAc)2 as a catalyst and Cu(OAc)2·H2O as an additive in DMSO/H2O as a key step followed by double N-arylation and cyclization.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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