Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5280870 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A simple and efficient total synthesis of ellipticine was developed via the Suzuki-Miyaura coupling of sterically sensitive 2-hydroxybenzeneboronic acid with a multifunctional aryl halide using Pd(OAc)2 as a catalyst and Cu(OAc)2·H2O as an additive in DMSO/H2O as a key step followed by double N-arylation and cyclization.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Takeo Konakahara, Y.B. Kiran, Yuri Okuno, Reiko Ikeda, Norio Sakai,