Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5281070 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
Regioselectivity in isoquinoline alkaloid synthesis is analyzed here. Our experiments have shown that substituents on the aromatic ring of the starting amine are determinant in isoquinoline synthesis. The use of dicyclohexylcarbodiimide in activating carboxylic acids for electrophilic aromatic substitution reactions is presented for the first time.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rodolfo Quevedo, Edwin Baquero, Mario Rodriguez,