Article ID Journal Published Year Pages File Type
5281070 Tetrahedron Letters 2010 5 Pages PDF
Abstract

Regioselectivity in isoquinoline alkaloid synthesis is analyzed here. Our experiments have shown that substituents on the aromatic ring of the starting amine are determinant in isoquinoline synthesis. The use of dicyclohexylcarbodiimide in activating carboxylic acids for electrophilic aromatic substitution reactions is presented for the first time.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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