| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281154 | Tetrahedron Letters | 2005 | 4 Pages |
A facile formal total synthesis of dragmacidin B, trans-dragmacidin C, and cis- and trans-dihydrohamacanthins A is presented. Our approach to these bis(indole) alkaloids involves a one-pot, four-step cross-coupling/deprotection sequence where complete halogen selectivity is observed. A related approach to access the dihydrohamacanthins is also described.
Graphical abstractThe facile formal total synthesis of dragmacidin B, trans-dragmacidin C, and cis- and trans-dihydrohamacanthins A is presented. Our approach to these bis(indole) alkaloids involves a one-pot, four-step cross-coupling/deprotection sequence where complete halogen selectivity is observed. A related approach to access the dihydrohamacanthins is also described.Download full-size image
