| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281269 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
A two-step convenient sequence for the synthesis of previously inaccessible mono-Boc-protected bis-N-heterocyclic alkyl substituted ether derivatives 4 is described. Mitsunobu protocol was applied to the preparation of pyridinyl ether precursor 5. The reduction of the electron rich pyridinyl system 5 has been achieved catalytically using the combination of PtO2-H2SO4 or PtO2-pTsOH under a hydrogen atmosphere maintained by a gas balloon at ambient temperature.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jianhua Chao, Mariam Israiel, Junying Zheng, Cynthia Aki,