| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281291 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Hydrogen-bonding activation of aromatic aldehydes by a TADDOL-derivative promotes the vinylogous aldol reaction of Chan's diene in moderate efficiency and enantioselectivity. Electron-poor aromatic aldehydes show an enhanced reactivity and a competing asymmetric hetero-Diels-Alder reaction takes place in comparable (or higher) yields and enantiomeric excesses.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rosaria Villano, Maria Rosaria Acocella, Antonio Massa, Laura Palombi, Arrigo Scettri,