| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281327 | Tetrahedron Letters | 2008 | 4 Pages |
Cu2O was found to be an efficient and economical metal catalyst in the Ullmann cross-coupling reaction of vinyl bromides with imidazole or benzimidazole. The system Cu2O/ethyl 2-oxocyclohexanecarboxylate showed high catalytic activity in MeCN at 80-90 °C. The reaction gave the corresponding coupling products in good to excellent yields.
Graphical abstractCu2O was found to be an efficient and economical metal catalyst in the Ullmann cross-coupling reaction of vinyl bromides with imidazole or benzimidazole. It showed high catalytic activity with the ligand ethyl 2-oxocyclohexanecarboxylate in MeCN at 80-90 °C and gave the corresponding products in good to excellent yields. The double bond geometry of the vinyl bromides was retained under the reaction condition.Download full-size image
