Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5281447 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
Novel isoxazolines and isoxazoles of N-substituted saccharin derivatives are synthesized in good yields by 1,3-dipolar cycloaddition of N-allyl or propargyl N-substituted saccharin with arylnitrile oxide under solvent-free microwave irradiation. In this process, the yields were significantly improved over conventional heating, without alteration of the selectivity. The regioselectivity as well as the nonthermal specific microwave effect are discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mahmoud Mabrour, Khalid Bougrin, Rachid Benhida, André Loupy, Mohamed Soufiaoui,