Article ID Journal Published Year Pages File Type
5281470 Tetrahedron Letters 2008 4 Pages PDF
Abstract

Organozinc reagents (organozinc halides, diorganozincs and mixed copper-zinc reagents) react with β-(allyloxy)-enoates via a radical-polar crossover process to afford substituted furans in one single synthetic step following a domino reaction involving Michael addition and carbocyclisation. Reversal of diastereoselectivity can be obtained varying the organometallic and/or the reaction conditions.

Graphical abstractDownload full-size image

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , ,