| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281594 | Tetrahedron Letters | 2010 | 4 Pages |
Abstract
A novel domino carbolithiation reaction of vinylidenecyclopropanes 1 with but-3-yn-2-one and 1-phenylprop-2-yn-1-one by treating with LDA in THF was observed to give the corresponding adducts in moderate to good yields. The scope and limitations as well as the plausible mechanism have been discussed on the basis of control experiments.
Graphical abstractA novel domino carbolithiation reaction of vinylidenecyclopropanes with but-3-yn-2-one and 1-phenylprop-2-yn-1-one by treating with LDA in THF has been disclosed in this Letter, providing the corresponding domino adducts in moderate to good yields.Figure optionsDownload full-size imageDownload as PowerPoint slide
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