Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5281597 | Tetrahedron Letters | 2010 | 5 Pages |
Abstract
An enantioselective synthesis of C2-symmetric bis-homoallylic aromatic and heteroaromatic diamines in 54-89% yields, in 73-94% de and ⩾98% ee has been achieved via the allylboration of the corresponding N,Nâ²-bis(trimethylsilyl)dialdimines and N,Nâ²-bis(diisobutylalumino)dialdimines with B-allyldiisopinocampheylborane in the presence of methanol, followed by alkaline hydrogen peroxide workup. One-pot synthesis of stable N,Nâ²-bis(benzaldimine-triethylborane) complexes and subsequent allylboration to afford benzene diamines is also described.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
P. Veeraraghavan Ramachandran, Debanjan Biswas, Marek P. Krzeminski, Guang-Ming Chen,