Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5281772 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
An efficient methodology for the synthesis of complex pyridin-3-yl-phenyl biaryl systems is described; microwave irradiation greatly enhances the rate of the two Pd-catalyzed key steps: formation of the stannane partner and its subsequent Stille coupling with a range of highly functionalized pyridines. Besides being fast and high yielding, this process also allows diversification of the pyridine at a late stage.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Véronique Dehlinger, Frédéric Cordier, Colin P. Dell, Nicolas Dreyfus, Nikki Jenkins, Adam J. Sanderson, Colin W. Smith,