Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5281773 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A general method for the preparation of diaza-spirocycles is reported. This method used an olefin metathesis in order to construct the desired spirocyclic framework. Beginning with commercially available protected amino ketones, this strategy ultimately produced pharmacologically relevant diaza-scaffolds in an efficient and high-yielding process.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vijaya Gracias, Alan F. Gasiecki, Joel D. Moore, Irini Akritopoulou-Zanze, Stevan W. Djuric,