| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281775 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
The one-pot bromo- and chloro-methylation of various 5-substituted salicylaldehydes with paraformaldehyde and hydrobromic or hydrochloric acid has been achieved. This approach establishes a convenient and flexible method to attach functional arms to salicylaldehydes for further applications in organic and coordination chemistry. Examples are described using 3-bromomethyl-5-t-butylsalicylaldehyde in the synthesis of piperazine-containing heteroditopic ligands as receptors for metal salts.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
