| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281857 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
We developed an efficient synthetic strategy of poly-substituted 1-arylisoquinolines via an indium-mediated Barbier type allylation from δ-ketonitriles. Initial attack of allylindium species occurred at the nitrile group selectively to form the enamine intermediate, which reacted with the ketone group intramolecularly to furnish the isoquinolines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sung Hwan Kim, Hyun Seung Lee, Ko Hoon Kim, Jae Nyoung Kim,