| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5281858 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
The reaction of Baylis-Hillman acetates and ethyl mercaptoacetate in the presence of DBU in DMF produced 2,3,4-trisubstituted tetrahydrothiophenes at room temperature as a diastereomeric mixture via the sequential SN2â² and Michael addition. Aromatization of tetrahydrothiophenes by DDQ oxidation produced 2,3,4-trisubstituted thiophenes in good yields.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hyun Seung Lee, Se Hee Kim, Jae Nyoung Kim,