Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5281938 | Tetrahedron Letters | 2008 | 4 Pages |
Abstract
The [3+2] cycloaddition between various nitriles and trimethylsilyl azide proceeds smoothly in the presence of a CuI catalyst in DMF/MeOH, to give the corresponding 5-substituted 1H-tetrazoles in good to high yields. The reaction most probably proceeds through the in situ formation of a copper azide species, followed by a successive [3+2] cycloaddition with the nitriles.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Tienan Jin, Fukuzou Kitahara, Shin Kamijo, Yoshinori Yamamoto,