Article ID Journal Published Year Pages File Type
5282006 Tetrahedron Letters 2006 5 Pages PDF
Abstract

A mild and efficient method for the synthesis of substituted thiazoles is reported via one-pot N-desilylation, thioacylation/oxythioacylation/thiothioacylation followed by thia-Michael cycloisomerisation. This method has a general applicability to introduce various oxo and thio functionalities including aliphatic and aromatic moieties, especially at the C2-position of thiazoles.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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