Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282006 | Tetrahedron Letters | 2006 | 5 Pages |
Abstract
A mild and efficient method for the synthesis of substituted thiazoles is reported via one-pot N-desilylation, thioacylation/oxythioacylation/thiothioacylation followed by thia-Michael cycloisomerisation. This method has a general applicability to introduce various oxo and thio functionalities including aliphatic and aromatic moieties, especially at the C2-position of thiazoles.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pradip K. Sasmal, S. Sridhar, Javed Iqbal,