Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282056 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Heating a neat 1:2 mixture of 2-picolylamine and 2-cyanopyridine, followed by treatment of the resultant red gummy substance with aqueous KOH resulted in the isolation of 2,4,5-tris(2-pyridyl)imidazole (1a) as the major product and N-(3-(2-pyridyl)imidazo[1,5-a]pyridine)picolinamidine (2a) in small amounts. Similarly, by using 3-picolylamine, 2,4,-bis(2-pyridyl)-5-(3-pyridyl)imidazole (1b) and N-(3-(3-pyridyl)imidazo[1,5-a]pyridine)picolinamidine (2b) were isolated, and by using 4-picolylamine, 2,4,-bis(2-pyridyl)-5-(4-pyridyl)imidazole (1c) and N-(3-(4-pyridyl)imidazo[1,5-a]pyridine)picolinamidine (2c) were isolated. The plausible mechanism of the formation of 1a-c and 2a-c is delineated.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Vijendra Kumar Fulwa, Rojalin Sahu, Himanshu Sekhar Jena, Vadivelu Manivannan,