Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282084 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A C-O-dianionic zincate was generated by a Te/Li exchange reaction of an alkyltelluride, followed by Li/Zn transmetallation and reaction with methyllithium. The reaction between the enantiomerically pure (99% ee) (R)-dianionic zincate and benzoyl chloride led to 3-hydroxy-1-phenyl pentanone with total retention of the carbon configuration (99% ee). Similar results were obtained using the corresponding Lipshutz cyanocuprates.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jefferson L. Princival, Alcindo A. Dos Santos, João V. Comasseto,