| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5282089 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
A concise and versatile formal synthesis to (+)-nephrosteranic acid was accomplished from a common nitroderivative 2 in a sequence of six steps. The adduct 2 was obtained via a highly syn-diastereoselective conjugate addition of 1-dodecyl nitronate ion to chiral enoate Z-5 (yield = 80%; de = 95%), derived from d-(+)-mannitol.
Graphical abstractDownload full-size image
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Cleber B. Jr., Vera L. Patrocinio Pereira,