Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282170 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Substitutions on the 2-position of the imidazole ring of histamine have proven useful in a number of biochemical settings. Current art for the synthesis of these constructs relies upon a cumbersome and low-yielding condensation reaction. Here-in we report a new procedure for the synthesis of a series of substituted 2-phenylhistamines utilizing a microwave-promoted Suzuki coupling.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Amanda P. Skoumbourdis, Susanna Moore, Marc Landsman, Craig J. Thomas,