Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282175 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
Reactions of pyrrolidine with 2 equiv of aldehydes without any catalyst in a pressurized vessel at 140-200 °C yielded 1,3-disubstituted pyrroles. α-Branched aldehydes gave fairly good yields of the corresponding products by this method, which provides a facile non-oxidative procedure for synthesizing 1,3-dialkylpyrroles from inexpensive pyrrolidine and aldehydes.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mitsunori Oda, Yosuke Fukuchi, Satoshi Ito, Nguyen Chung Thanh, Shigeyasu Kuroda,