| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5282262 | Tetrahedron Letters | 2006 | 6 Pages |
Abstract
A facile and versatile method for the chemoselective Boc protection of amines has been developed by a treatment with (Boc)2O in the presence of sulfonic-acid-functionalized silica as a catalyst. The method is general for the preparation of N-Boc derivatives of aliphatic (acyclic and cyclic), aromatic, and heteroaromatic amines; primary and secondary amines; aminols, amino-esters; and sulfonamides. The catalyst works under heterogeneous conditions and can be recycled.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Biswanath Das, Katta Venkateswarlu, Maddeboina Krishnaiah, Harish Holla,