Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282313 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Under microwave irradiation, perbenzylated pyranoid glycals were coupled with aryl bromides in the presence of 5% mol palladium(II) acetate in dimethylformamide to produce 2â²,3â²-unsaturated C-aryl-α-glycopyranosides in a rapid and stereospecific manner. The synthetic applicability of the method was further demonstrated by converting the resulting C-aryl glycosides to 2â²-deoxy C-aryl-β-glycopyranosides through oxidation mediated by 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) and stereoselective reduction.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ming Lei, Liang Gao, Jin-Song Yang,