Article ID Journal Published Year Pages File Type
5282483 Tetrahedron Letters 2006 6 Pages PDF
Abstract
The first total synthesis of a spiro-isoquinoline alkaloid, (±)-annosqualine, was established by employing an enamide-phenol coupling of an isoquinoline derivative with a hypervalent iodine reagent, as a key step.
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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
The first total synthesis of (±)-annosqualine by means of oxidative enamide-phenol coupling: pronounced effect of phenoxide formation on the phenol oxidation mechanism
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