| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5282520 | Tetrahedron Letters | 2009 | 4 Pages |
Abstract
Chiral phosphine oxide successfully catalyzed the direct aldol-type reactions of cyclohexanone derivatives and benzaldehyde derivatives in high stereoselectivities. The reaction mechanism involves the in situ formation of trichlorosilyl enol ethers. The present reaction could be extended to the cross-aldol reactions between two aldehydes.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shunsuke Kotani, Yasushi Shimoda, Masaharu Sugiura, Makoto Nakajima,