| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5282785 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
Samarium diiodide is an efficient precatalyst for the Friedel-Crafts reaction involving various aromatic substrates and chelating electrophiles. Alkyl 3,3,3-trifluoropyruvates are transformed into α-hydroxyesters in good yields with total regioselectivity. In reactions involving an ethyl glyoxylate or a glyoxylic imine, α-hydroxyesters or α-aminoesters are obtained with variable amounts of products resulting from a double Friedel-Crafts reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mohamad Soueidan, Jacqueline Collin, Richard Gil,