| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5282948 | Tetrahedron Letters | 2007 | 4 Pages |
Abstract
We report the synthesis of an adenosyl-derived indolylphosphonamide analogue of salicyladenosylmonophosphate involved in the plague and tuberculosis siderophore biosyntheses. The compound proved to be a potent inhibitor of the Yersinia pestis salicylate adenylation domain YbtE catalyzing the initial step of yersiniabactin biosynthesis.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Philippe Bisseret, Sabine Thielges, Stéphane Bourg, Marcus Miethke, Mohamed A. Marahiel, Jacques Eustache,