Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5282953 | Tetrahedron Letters | 2007 | 5 Pages |
Abstract
An efficient protocol for aza-Michael addition of aromatic N-heterocycles to α,β-unsaturated compounds has been described. The reaction was catalyzed by promiscuous zinc-active-site acylase in organic solvent at 50 °C and most of the procedures could provide products in good yields in several hours (0.5-6 h).
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chao Qian, Jian-Ming Xu, Qi Wu, De-Shui Lv, Xian-Fu Lin,