Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5283074 | Tetrahedron Letters | 2006 | 4 Pages |
Abstract
A cyclophane-based resorcinarene tetramer, which is constructed with a tetraaza[6.1.6.1]paracyclophane and four resorcinarenes bearing hepta(carboxylic acid) residues that connect the macrocycle through amide linkages, was prepared. The binding constant of the cyclophane-based resorcinarene with immobilized histone was determined to be 1.3Â ÃÂ 107Â Mâ1 by surface plasmon resonance measurements, which was 31-fold larger than that of the resorcinarene monomer bearing octacarboxylic acids. Moreover, the cyclophane-based tetra(resorcinarene) acted as a host toward hydrophobic molecular guests such as 6-p-toluidinonaphthalene-2-sulfonate.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Osamu Hayashida, Masaki Uchiyama,